Adipotide.
About Adipotide
Adipotide is among the compounds studied in metabolic and weight-regulation research. Binds prohibitin on the vasculature supplying white adipose tissue and triggers targeted apoptosis of those blood vessels, cutting off the blood supply to fat depots.
Research Application
In preclinical models, adipotide produced marked fat-mass reduction (including roughly 11% body-weight reduction in obese rhesus monkeys after 28 days). Because of renal toxicity observed in humans, it is now regarded strictly as a research tool with no clinical pathway forward.
Important to know
Claims circulating online are often not backed by valid clinical data. Treat all information as a starting point for your own scientific research, not as usage guidance.
Sequence and regulatory status data are based on publicly available sources and refer to the compound in general, not to a specific product.
Research Overview
A growing number of preclinical and clinical studies exist for metabolic peptides, though the volume varies significantly by substance.
- Kolonin MG, et al. Nat Med. 2004;10(6):625–632. PMID 15133506
- Barnhart KF, et al. Sci Transl Med. 2011;3(108):108ra112. PMID 22072637
References without a PMID can be located via the respective publisher. This overview does not claim to be exhaustive.
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