5-Amino-1MQ is studied in research on cellular energy metabolism and longevity. 5-Amino-1MQ selectively inhibits nicotinamide N-methyltransferase (NNMT), an enzyme that methylates nicotinamide while consuming SAM. NNMT inhibition raises intracellular NAD+ and SAM levels while suppressing lipogenesis in adipocytes.
Studied preclinically in diet-induced obesity research: the compound reduced body weight and fat mass in diet-induced obese mice without altering food intake.
Claims circulating online are often not backed by valid clinical data. Treat all information as a starting point for your own scientific research, not as usage guidance.
Sequence and regulatory status data are based on publicly available sources and refer to the compound in general, not to a specific product.
Research on longevity and energy metabolism is primarily supported by preclinical data.
References without a PMID can be located via the respective publisher. This overview does not claim to be exhaustive.
We reply personally – via email or Telegram.