VIP is studied in the context of neuroscience and cognitive research. Binds the G-protein-coupled receptors VPAC1 and VPAC2, activating cAMP-dependent signaling; produces vasodilation, modulates the circadian pacemaker function of the suprachiasmatic nucleus, and exerts broad immunomodulatory effects.
A central research subject in neuroimmunology and chronobiology, and — as aviptadil — in clinical trials for acute respiratory failure in COVID-19.
Claims circulating online are often not backed by valid clinical data. Treat all information as a starting point for your own scientific research, not as usage guidance.
Sequence and regulatory status data are based on publicly available sources and refer to the compound in general, not to a specific product.
Studies on neuroscience-related peptides are predominantly preclinical.
References without a PMID can be located via the respective publisher. This overview does not claim to be exhaustive.
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