Regeneration

B7-33.

Available Variants

6 mg

View lab reports Quality process

Research area: Regeneration

🛡️

For research purposes only. Not intended for use in humans or animals.

Regeneration research

About B7-33

B7-33 wird in der Forschung im Bereich Geweberegeneration und -reparatur untersucht, u. a. in Zell- und Tiermodellen. Wirkt als funktionsselektiver Partialagonist am RXFP1-Rezeptor: Es aktiviert bevorzugt den pERK1/2-MMP2-Signalweg anstelle des klassischen cAMP-Signalwegs des vollständigen Relaxins, wodurch antifibrotische Effekte erzielt werden.

Research Application

Used in cardiovascular and pulmonary research to study organ fibrosis and tissue remodeling, and as a tool to investigate receptor-selective GPCR signaling.

Important to know

Claims circulating online are often not backed by valid clinical data. Treat all information as a starting point for your own scientific research, not as usage guidance.

Content 6 mg

Form Lyophilized powder

Category Regeneration

Purity & Identity see lab reports →

Sequence / Structure A linear, single-chain 20-amino-acid peptide derived solely from the B-chain of human relaxin-2 (H2 relaxin) — unlike the native, cyclic two-chain hormone.

Regulatory Status Preclinical research only, in rodent models (cardiac and pulmonary fibrosis). No registered human trials found. Developed by research groups at Monash University and the Florey Institute.

Sequence and regulatory status data are based on publicly available sources and refer to the compound in general, not to a specific product.

Research Overview

Studies on regenerative peptides are mostly derived from cell culture and animal models; comprehensive clinical data is typically still limited.

Hossain MA, et al. Chem Sci. 2016;7(6):3805–3819. PMID 30155023

References without a PMID can be located via the respective publisher. This overview does not claim to be exhaustive.

Similar Peptides

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