SS-31.
About SS-31
SS-31 is studied in research on cellular energy metabolism and longevity. SS-31 accumulates strongly and selectively at the inner mitochondrial membrane, where it binds cardiolipin, a phospholipid essential for cristae structure. This stabilizes cristae architecture, improves ATP production, and reduces oxidative stress.
Research Application
The TAZPOWER trial (Barth syndrome) showed significant improvements in skeletal muscle strength and cardiac stroke volume over 48 weeks — the basis for the later FDA approval. Also under investigation in heart failure and age-related muscle decline research.
Important to know
Claims circulating online are often not backed by valid clinical data. Treat all information as a starting point for your own scientific research, not as usage guidance.
Sequence and regulatory status data are based on publicly available sources and refer to the compound in general, not to a specific product.
Research Overview
Research on longevity and energy metabolism is primarily supported by preclinical data.
- Zhao K, et al. J Biol Chem. 2004;279(33):34682–34690. PMID 15178689
- Thompson WR, et al. Genet Med. 2021;23(3):471–478.
References without a PMID can be located via the respective publisher. This overview does not claim to be exhaustive.
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