Focus

Kisspeptin-10.

Available Variants

5 mg 10 mg

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Research area: Focus

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For research purposes only. Not intended for use in humans or animals.

Neuroscience research

About Kisspeptin-10

Kisspeptin-10 is studied in the context of neuroscience and cognitive research. The most potent known activator of the hypothalamic-pituitary-gonadal axis: binds GPR54 on hypothalamic GnRH neurons and triggers pulsatile GnRH release, which stimulates pituitary LH and FSH secretion.

Research Application

A central tool in reproductive endocrinology research on puberty onset and GnRH pulse-generator physiology; also studied in oncology research on tumor invasion and cardiovascular research on vascular tone.

Important to know

Claims circulating online are often not backed by valid clinical data. Treat all information as a starting point for your own scientific research, not as usage guidance.

Content 5 mg, 10 mg

Form Lyophilized powder

Category Focus

Purity & Identity see lab reports →

Sequence / Structure Decapeptide H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2, the C-terminal amidated fragment (residues 45–54) of KISS1-gene-encoded metastin/kisspeptin-54. Binds the receptor GPR54 (KISS1R) with higher affinity than the full-length peptide.

Regulatory Status Not an approved drug; used as a research compound in reproductive endocrinology and oncology research, including short-term investigational intravenous administration in human studies.

Sequence and regulatory status data are based on publicly available sources and refer to the compound in general, not to a specific product.

Research Overview

Studies on neuroscience-related peptides are predominantly preclinical.

Seminara SB, et al. N Engl J Med. 2003;349(17):1614–1627.
Cho SG, et al. Cancer Res. 2009;69(17):7062–7070.

References without a PMID can be located via the respective publisher. This overview does not claim to be exhaustive.

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