Focus

P21.

Available Variants

10 mg

View lab reports Quality process

Research area: Focus

🛡️

For research purposes only. Not intended for use in humans or animals.

Neuroscience research

About P21

P21 is studied in the context of neuroscience and cognitive research. Activates downstream CNTF signaling without the appetite-suppressing effect of full-length CNTF; raises BDNF expression, proposed to inhibit GSK-3β via the TrkB/PI3K/Akt pathway and thereby reduce tau hyperphosphorylation.

Research Application

A preclinical research tool in Alzheimer's and tauopathy models for studying neurogenesis and tau-related pathology; the evidence base remains thin and concentrated in a small number of laboratories.

Important to know

Claims circulating online are often not backed by valid clinical data. Treat all information as a starting point for your own scientific research, not as usage guidance.

Content 10 mg

Form Lyophilized powder

Category Focus

Purity & Identity see lab reports →

Sequence / Structure A small synthetic peptidomimetic derived from the active loop region of ciliary neurotrophic factor (CNTF) — despite common vendor naming, NOT a BDNF mimetic but a CNTF-loop mimetic that increases downstream BDNF expression.

Regulatory Status Ausschließlich präklinisch (Nagetiermodelle); keine publizierten Daten aus klinischen Studien am Menschen. Die Forschung stammt überwiegend aus dem Labor von Khalid Iqbal (New York State Institute for Basic Research), publiziert unter der Bezeichnung „P021".

Sequence and regulatory status data are based on publicly available sources and refer to the compound in general, not to a specific product.

Research Overview

Studies on neuroscience-related peptides are predominantly preclinical.

Specific study references will be added for this product. For current literature, independent research (e.g. via PubMed) is recommended.

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