GHRP-6 is among the peptides researched in the context of the growth hormone (GH) axis. GHRP-6 activates the ghrelin receptor (GHS-R1a) in the pituitary and hypothalamus, and is additionally associated with binding to CD36 in cardiac tissue — a pathway independent of the GH axis.
As the first synthetic growth-hormone-releasing peptide, GHRP-6 is studied in GH-axis research. The additionally described CD36 binding mechanism in cardiac tissue is discussed independently of the growth hormone effect.
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Sequence and regulatory status data are based on publicly available sources and refer to the compound in general, not to a specific product.
Numerous preclinical and some clinical studies exist on the GH axis, with evidentiary strength varying by substance.
References without a PMID can be located via the respective publisher. This overview does not claim to be exhaustive.
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