EPO.
About EPO
EPO is studied in research on cellular energy metabolism and longevity. EPO binds the classical erythropoietin receptor to stimulate erythropoiesis in bone marrow. It also activates a distinct tissue-protective receptor complex, triggering anti-apoptotic signaling independent of blood formation — the basis for ARA-290, a non-hematopoietic peptide fragment engineered from EPO's structure, listed separately on this site.
Research Application
Firmly established in clinical practice for renal and chemotherapy-induced anemia. In research, native EPO also serves as the reference molecule for developing non-hematopoietic, tissue-protective fragments such as ARA-290.
Important to know
Claims circulating online are often not backed by valid clinical data. Treat all information as a starting point for your own scientific research, not as usage guidance.
Sequence and regulatory status data are based on publicly available sources and refer to the compound in general, not to a specific product.
Research Overview
Research on longevity and energy metabolism is primarily supported by preclinical data.
- Eschbach JW, Adamson JW. PMID 2690606
- Brines M, et al. Proc Natl Acad Sci U S A. 2008;105(31):10925–10930. PMID 18676614
References without a PMID can be located via the respective publisher. This overview does not claim to be exhaustive.
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